Archives : Sep, 2023

Archives : Sep, 2023

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RecruitsThere is no open position.

1. HDO Structure

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1. HDO Structure

HDO is composed as follows. Antisense strand (DNA, Gapmer, PMO etc.): Has a medicinal effectCarrier strand (RNA): Transport active strand (medicina

①Licensing

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①Licensing

This is our business structure for licensing out HDO technology.

②Collaborative R&D

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②Collaborative R&D

This is our business structure or collaborative R&D with customers, in which Rena designs and provides HDO compounds and moves collaborative R&D forw

③HDO manufacturing

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③HDO manufacturing

This is our business structure for the HDO manufacturing business in which Rena manufactures,supplies and sells HDOs for target genes only for resear

 Message

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 Message

 Company Philosophy

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 Company Philosophy

 Company Information

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 Company Information

 Introduction of Board of Directors

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 Introduction of Board of Directors

2. HDO Mechanism of Action(1)

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2. HDO Mechanism of Action(1)

(RNse H-dependent antisense effect)Step 1The HDO carrier strand (RNA) incorporated into the cell is cleaved by RNase H (enzyme).Step 2The antisens

3. HDO Mechanism of Action(2)

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3. HDO Mechanism of Action(2)

(Splicing Control)Step 1HDO enters the cell through some special ligand into the cells.Step 2The carrier stand cleaved by RNase.Step 3The antise

4. Strengths of HDO technology

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4. Strengths of HDO technology

HDO has the following strengths:By linking the ligand to the carrier strand, it is possible to selectively deliver the antisense strand to the diseas